Optilab differential refractive index (dRI) detectors are utilized primarily for on-line measurement of analyte concentration in SEC-MALS and FFF-MALS, and for determination of analyte dn/dc (refractive index increment), and the absolute refractive index (aRI) of solvents.
Optilab® dRI detectors serve as universal concentration detectors since no chromaphore or fluorophore is necessary. Required for Conjugation Analysis.
The Optilab® T-rEX
Universal Detection for Chromatography and FFF Separations
Independent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors serve as accurate and versatile concentration detectors in all types of solvents. dRI is part of standard instrumentation for a variety of macromolecular characterization techniques including standard chromatography, SEC-MALS, FFF-MALS and CG-MALS.
The Optilab® T-rEX (refractometer with EXtended range) is a unique dRI detector for standard HPLC/GPC with 256 times the detection power and 50 times the dynamic range of every other RI detector for chromatography in existence today, making it a valuable addition to any MALS setup.
Independent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors measure concentrations of all types of samples in almost all solvents. The Optilab® UT-rEX brings the universal detection capabilities, unsurpassed concentration range, and superb sensitivity and linearity – familiar from the Optilab T-rEX – to the domain of UHPLC.