TOYOPEARL® and TSKgel® chromatography resins

TOYOPEARL® chromatography resins are hydrophilic, macroporous, bulk processing media designed especially for large-scale chromatography applications. TOYOPEAR®L resins are available for the most common modes of liquid chromatography: size exclusion (SEC), hydrophobic interaction (HIC), ion exchange (IEC) and Affinity chromatography (AFC).

Based on their semi-rigid backbone structure TOYOPEARL® resins assure excellent pressure/flow characteristics. TOYOPEARL® is stable over the pH 2-13 range. Particle sizes are 20-40 µm superfine grade (S) for the highest performance, 40-90 µm for economical purification (M), and 90-120 µm coarse grade (C) and 100 – 300 µm extra coarse grade (EC) for the largest scale chromatography.Similar Chemistries of TOYOPEARL® and TSKgel® columns allow seamless scale up. TOYOPEARL® polymeric resins are available as bulk resin and in prepacked ToyoScreen® columns for convenient screening.


Tosoh Bioscience tilbyder en omfattende linje af resiner til alle slags behov for oprensning.

  • Toyopearl HW og TSKgel PW size exclusion resiner er basispartikler for hele Tosohs ion exchange, hydrophobic interaction og affinity produkter.
    Protein A-affinitetskromatografi er det mest populære redskab til oprensning af antistoffer fra cellekultur lysater, da det kan opnå en renhed på mere end 95% i ét kromatografisk trin.
  • TOYOPEARL AF-rProtein A HC-650F opnår dynamiske bindingskapaciteter større end 65 mg/L ved opholdstid i kolonnen på 5 minutter, og større end 50 mg/mL ved opholdstid i kolonnen på 2 minutter med koncentration af råvare fra 1 g/L til mere end 10 g/L.

Gå til Tosoh Bioscience’s hjemmeside for en samlet oversigt over alle resiner.


For flere detaljer og pris, kontakt venligst MD Scientific via e-mail: info@md-scientific.dk eller telefon: 7027 8565.


  • TOYOPEARL and TSKgel Process Media
    TSKgel and TOYOPEARL resins are specifically designed for use in biopharmaceutical production. Based on a rigid polymer structure, they show excellent physical strength and flow characteristics, resulting in faster process throughput. Optimized pore diameters and narrow particle size distribution allow rapid kinetics and exceptional resolution.
    TOYOPEARL and TSKgel resins are applied from capture, through intermediate purification, to polishing. Target molecules range from peptides and proteins to oligonucleotides and plasmids. To support the use of the resins in a regulated environment, “regulatory support files” are available.
    In this section, you can locate the resin that is best suited for your application by chromatography mode or process step. Just select from any of the links listed below for a short tutorial on the mode or on the process steps as well as the variety of TOYOPEARL and TSKgel resins offered.


Process Step

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